In practice, experimental techniques can measure the time and space average properties but they cannot be captured the structural variation of the COVID-19 during the interaction of inhibitor.
#Death note rules 1 10 trial#
Thousands of compounds including approved drugs and drugs in the clinical trial are available in the literature. Therefore, a protocol to identify anti-COVID-19 candidate based on computer-aided drug design is urgently needed. Predicting inhibitor and target to the COVID-19 is an urgent need to protect human from the disease. At this moment only few Asian countries have controlled the disease, but a second wave of new infections is expected. Infected people in Europe and America correspond about 40% and 30% of the total reported cases respectively.
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As of 15 April 2020, The Johns Hopkins University estimated that the COVID-19 affected more than two million people, resulting in a death toll above 130,000 around the world.
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Most recently, the global outbreak of novel coronavirus 2019 (SARS-CoV-2) that causes COVID-19 is a newly discovered virus from the coronavirus family in Wuhan city, China, known to be a great threat to the public health systems. Ebola, Influenza A (H1N1), SARS, MERS, and Zika virus have had a massive global impact in terms of economic disruption, the strain on local and global public health. In the past two decades, the world has faced several infectious disease outbreaks.